In the End User Computing (EUC) space we know that after the first time the application starts post reboot, the next time is faster. The first startup is referred to as a cold startup and all subsequent runs are warm startups. The first time the application starts, components of the application, such as the EXEs (executables) and DLLs (dynamic link libraries) need to be loaded from disk, which can delay the startup time. All subsequent runs will then read the data from the file system cache, which is memory managed by the Operating System.
The way we prepare a system for a user is to cold start (pre-launch) the applications when the system starts. We do this by starting and then terminating each process, such as winword.exe.